Wait, really?
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1. The iPhone
2. 9/11
3. Facebook
9/11
Barack Obama
MJ's death.
9/11
Wiki-leaks
Rise of the reality TV show.
1st: The Iraq war. It changed the entire perception of the USA, and our own government and still haunts various politicians today.
2nd: 9/11. Safe to say Air Travel has definately been changed all over the world (assuming you are patient enough to get onto the damn plane :P)
3rd: The rise of the internet as mainstream and a community, with the ability to swing votes an have quite a lot of influence.
1. Stillmatic
2. The rise of Chelsea FC (although it really started in '96)
3. HxF