Originally Posted by
Biohazard
Nope, the numbers were the core numbers in the Valenzetti Equation (which is the prediction of the end of the world, created by Valenzetti on the island, hired by Hanso for the Dharma Initiative), and they were looped on the radio tower so someone could find away to change them, and therefore change the end of humanity. This is actually canon, yet wasn't described (much) in the episodes themselves.
But it was never explained the relevance to them and everything else to do with Hurley etc. and why they kept appearing everywhere.